Course Syllabus

Biological Chemistry 650 - Eukaryotic Gene Transcription
Lectures: Fri 10 am - 12 noon in 4560C MSRB II
Drs Dan Bochar, Yali Dou, Raymond Trievel, and Tom Kerppola (Course Director)

Sep. 12      Introduction/Core transcription factors (Kerppola/Bochar)

Sep. 19      Transcription initiation (Bochar)

Sep. 26      RNA-Pol II structure/elongation (Trievel)

Oct. 3        Higher order chromatin structures and chromatin remodeling (Trievel/Bochar)

Oct. 10      Chromatin modifications (Dou)

Oct. 24      Chromatin modifying enzymes (Dou)

Oct. 31      Chromatin binding proteins (Dou)

Nov. 7       Transcription silencing and small RNAs (Dou)

Nov. 14     DNA methylation (Dou)

Nov. 21     From the genome to the transcriptome (Kerppola)           

Nov. 28     Transcription regulatory elements and proteins (Kerppola)

Dec. 5        Transcription factor interactions and combinatorial regulation (Kerppola)

Dec. 12      Spatial organization of the nucleus and the genome (Kerppola)

Dec. 19      Final paper deadline