Course Syllabus

Biological Chemistry 650 - Eukaryotic Gene Transcription
Lectures: Fri 10 am - 12 noon in 4560C MSRB II
Drs Dan Bochar, Yali Dou, Raymond Trievel, and Tom Kerppola (Course Director)

Sep. 12      Introduction/Core transcription factors (Kerppola/Bochar)

Sep. 19      Transcription initiation (Bochar)

Sep. 26      RNA-Pol II structure/elongation (Trievel)

Oct. 3        Higher order chromatin structures and chromatin remodeling (Bochar)

Oct. 10     What is a gene? How is it transcribed? (Kerppola)

Oct. 19      10-11:30 am Optional help session (Kerppola)

Oct. 24      What DNA sequences regulate transcription? (Kerppola)
-deadline to select a paper for critical review

Oct. 31     Transcription factor interactions and genome organization (Kerppola)

Nov. 7       Student presentations (Kerppola)

Nov. 14     Chromatin modifications (Dou)

Nov. 21     Chromatin modifying enzymes (Dou)
- deadline to submit a polished draft for the critical review

Nov. 28     Chromatin binding proteins (Dou)

Dec. 5        Transcription silencing and small RNAs (Dou)

Dec. 12      DNA methylation (Dou)
- deadline to submit your critical review